The Trump administration has successfully negotiated substantial price reductions for 15 widely prescribed medications covered under Medicare, marking a significant development in the ongoing effort to address prescription drug costs for American seniors.

The Centers for Medicare and Medicaid Services announced Monday that the negotiated prices represent a 44 percent reduction in spending on these medications, totaling approximately $12 billion in savings for the federal program. The discounts, which range from 38 percent to 85 percent off list prices, will take effect in 2027 for medications purchased through Medicare’s Part D prescription plan.

The negotiations were conducted under provisions of the Inflation Reduction Act of 2022, which ended a longstanding prohibition preventing Medicare from negotiating directly with pharmaceutical manufacturers. Prior to this legislation, the government health program was required to accept whatever prices drug companies established.

The 15 medications covered under the new agreement include several well-known treatments. Among them are Novo Nordisk’s Ozempic and Wegovy, medications widely prescribed for diabetes management and weight loss. Other drugs on the list address common conditions including asthma and prostate cancer.

According to CMS, approximately 5.3 million Medicare Part D enrollees currently use these medications, which account for $40.7 billion in program spending. The agency projects that the 55 million people enrolled in Part D will collectively save roughly $685 million under the new pricing structure.

The question of how these negotiations will affect individual seniors remains somewhat complex. Medicare enrollees are already protected by an out-of-pocket spending cap introduced through the same legislation. Beginning in 2025, this cap was set at $2,000 annually, with adjustments for inflation that could bring it to approximately $2,200 by 2027. Once beneficiaries reach this threshold, they pay nothing for covered prescriptions.

The practical impact for individual seniors will depend on several factors, including which medications they use and whether they reach their annual spending limit. Based on the number of people using these drugs and the projected total savings, the average reduction would amount to roughly $129 per Medicare enrollee. However, actual savings will vary considerably depending on individual circumstances.

Beyond the immediate benefit to seniors who have not yet reached their spending cap, these negotiations represent a broader fiscal achievement for the Medicare program itself. The substantial reduction in drug spending strengthens the program’s financial position and demonstrates the potential impact of allowing direct price negotiations with pharmaceutical manufacturers.

The cost of prescription medications has consistently ranked among the primary concerns of American seniors. This development addresses that concern through a straightforward approach: using the federal government’s purchasing power to secure more favorable terms for one of the nation’s largest health programs.

The new prices will apply to medications purchased through Medicare Part D beginning in 2027, giving both the program and pharmaceutical companies time to adjust to the new pricing structure. The medications covered represent some of the most expensive and widely used drugs within the Medicare system, making them logical targets for initial negotiation efforts.

This represents the first round of such negotiations under the new authority granted by Congress. The long-term effects on both Medicare’s finances and individual beneficiaries will become clearer as the implementation date approaches.

Related: National Guard Members Wounded in Shooting Near White House